منابع مشابه
Cytomegalovirus infection in brain tumors
Emerging evidence demonstrate a high prevalence of cytomegalovirus (CMV) proteins and nucleic acids in different tumors. CMV is confined to tumor cells and non-cancer cells in close proximity to tumors are consistently virus negative. CMV confers both oncogenic and oncomodulatory mechanisms, and may therefore provide a novel target in cancer treatment.
متن کاملAbsence of human cytomegalovirus infection in childhood brain tumors.
Human cytomegalovirus (HCMV) is a common human pathogen which induces different clinical manifestations related to the age and the immune conditions of the host. HCMV infection seems to be involved in the pathogenesis of adult glioblastomas. The aim of our study was to detect the presence of HCMV in high grade gliomas and other pediatric brain tumors. This hypothesis might have important therap...
متن کاملFrequency of Cytomegalovirus (CMV) in benign and malignant tumors
Cytomegalovirus (CMV) is a widespread pathogen that is found in milk, saliva, urine, cervical secretions, and semen fluid. It is supposed that CMV is a risk factor for breast cancer. The aim of this study was to determine the frequency of CMV among benign and malignant breast tumors. Paraffin embedded breast carcinoma (n=24) and fibroadenoma (n=24) samples were collected from Toos and Firoozgar...
متن کاملdetection of hcmv infection in glioma brain tumors
objective: human cytomegalovirus (hcmv) is a beta-herpesvirus that causes persistent infection in humans, as well as severe disease in fetuses and immunocompromised individuals. although hcmv is not currently causally implicated in human cancer, emerging evidence suggests that hcmv infection may be specifically associated with malignancies such as gliomas. gliomas are one of the most common bra...
متن کاملSeroprevalence of Cytomegalovirus Infection in Blood Donors in Khorramabad
Background and Aims: Cytomegalovirus (CMV) has worldwide distribution, and its prevalence rate depends on factors such as economic and geographical conditions. An important way of the virus transmission is via blood. Due to high prevalence of anti-CMV antibodies in blood donors and lack of data concerning its seroprevalence in the region, this study was carried out to determine the prevalence r...
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ژورنال
عنوان ژورنال: OncoImmunology
سال: 2012
ISSN: 2162-402X
DOI: 10.4161/onci.19441